I have chronic prostatitis / chronic pelvic pain syndrome
Collins, RN, ND. Clinical observations and literature review both affirm the conviction that providing "systemic enzyme support," using Wobenzym N or Wobenzym PS, is an essential component in successfully managing inflammation disorders and other conditions with immune system dysregulation. In addition to improving clinical outcomes in conditions with Phlogenzym Prostatitis inflammation, such as rheumatoid arthritis, thrombophlebitis, pyelonephritis, prostatitis, and Phlogenzym Prostatitis, systemic enzyme support is also effective in conditions with covert inflammation, such as osteoarthritis, angina, atherosclerosis, myocardial infarctions, and diabetes, Phlogenzym Prostatitis name a few.
The adjuvant properties of systemic enzyme support have also been observed and documented for a number of Phlogenzym Prostatitis including adnexitis, arthritis, papillomas and various forms of cancer.
This article will familiarize clinicians with the therapeutic benefits of systemic enzyme support and review pertinent findings related to this treatment. Systemic Enzyme Support Formulations A significant amount of the published international literature describing the clinical benefits of systemic enzyme support is based on various formulations made for many decades by MUCOS Pharma, a Germany pharmaceutical company. The history of Wobenzym is significant in Phlogenzym Prostatitis systemic enzyme support requires sophisticated processing techniques to be effective.
Systemic enzyme support formulations are considered prescription drugs in part of Europe, and manufactured to the same high standards as pharmaceuticals. The Wobenzym N and Wobenzym PS animal enzyme, plant enzyme, and rutosid combinations are the most researched systemic enzyme formulations in the world, used by athletes, doctors and millions of others to help normalize inflammation, speed recovery from sports and other routine injuries, and promote healthy circulation.
The active constituents in Wobenzym N and Wobenzym PS are delivered through tablets that have a special enteric coating which can withstand the acid environment Phlogenzym Prostatitis the stomach, which is important since enzymes can be damaged by stomach acid.
Once the tablet has passed a safe distance from the stomach acids, it dissolves and the enzymes are efficiently absorbed by the mucosal membrane of the intestine.
This process is most effective if the tablets are taken away from meals. Inflammation Observed Enzymes are biological molecules that increase the rate of chemical reactions.
In the human body, thousands of chemical reactions occur during the course of normal metabolic processes. These reactions require significant energy in order to take place. Enzymes act as catalysts to lower the energy needed for the reaction to move forward.
As Phlogenzym Prostatitis, enzymes maintain optimal function of the various systems in the body and support overall good health and optimal quality of life. The immune system is very dependent on proper enzyme function in regard to regulating inflammation as well as protecting cells from damage.
Cytokine activity, and the clearance of excessive inflammatory cytokines, is regulated by proteases, enzymes which degrade proteins. The clearance of tissue proteins and peptides damaged by inflammation is also mediated by proteases. Proteases significantly reduce concentrations of advance glycation end-products AGEs and protect cells by decreasing their Phlogenzym Prostatitis RAGE activation.
Proteases also downregulate adhesion molecule activity in inflamed as well as malignant cells. This inflammation response can be quite aggressive, and manifest as the five cardinal signs of inflammation recognized ages ago: redness, heat, Phlogenzym Prostatitis, pain and loss of function, classically referred to in Latin as rubor, calor, tumor, dolor, and functio laesa.
These symptoms diminish Phlogenzym Prostatitis of life and may portend serious disease. Therefore, clinically evident inflammation is often recognized as the body's communicating an inability to control proper cellular processes. In addition to the clinical signs of inflammation, laboratory tests often show increased levels in the various biomarkers of inflammation that are also associated with increased morbidity and mortality.
Excessive fibrin activity and Phlogenzym Prostatitis amyloid beta-peptide can also be quantified in the presence of imbalanced inflammation. Certain cytokine levels may also increase, which may cause further imbalance in the immune system. The change in certain cytokine levels is of specific interest because it allows us to recognize when the immune system has become significantly imbalanced, and elucidates how immunomodulation can be achieved through the use of systemic enzymes.
Inflammation and Cytokines Phlogenzym Prostatitis are signaling proteins and glycoproteins involved in cellular communications that play a dominant role in maintaining the normal inflammatory processes of the immune system. They are produced Phlogenzym Prostatitis a Phlogenzym Prostatitis variety of cells and are typically subdivided into two categories, Phlogenzym Prostatitis and Th2. A balance Phlogenzym Prostatitis Th1 and Th2 responses is best Phlogenzym Prostatitis optimal health.
Th1 cytokines tend Phlogenzym Prostatitis produce the pro-inflammatory responses involved in antibacterial, antiviral, and antifungal responses.
Excessive Th1 responses can lead to uncontrolled tissue damage and may perpetuate autoimmune responses. A relative excess in Th1 is also observed in acute inflammation. Th2 cytokines tend to produce anti-inflammatory responses and can counteract the Th1-mediated microbicidal actions. Phlogenzym Prostatitis TH2 responses are associated with allergies Phlogenzym Prostatitis atopy asthma, eczema, allergic rhinitis, and allergic conjunctivitis.
A Phlogenzym Prostatitis excess in Th2 is also observed in chronic inflammation. The binding and removal of excessive cytokines Phlogenzym Prostatitis mediated by amacroglobulin alpha 2-macroglobulina naturally occurring high-molecular-weight plasma glycoprotein. Proteases bind with amacroglobulins to create amacroglobulin-protease complexes and transform the amacroglobulin from its native form into the active form.
The newly activated amacroglobulin-protease complex now has increased binding capacity for certain cytokines, as well as other proteins and glycoproteins. Therefore, these complexes, as well as the cytokines and debris they carry, are Phlogenzym Prostatitis removed by hepatic a-2M-receptors a-2M-R 5, and other cells expressing a-2M-R, such as macrophages. Since excessive cytokines Phlogenzym Prostatitis involved in autoaggressive inflammatory processes, the Phlogenzym Prostatitis to cytokines and the removal of cytokines by the activated amacroglobulin proteins support a balanced and properly functioning immune system.
Once cytokine levels are restored to their optimal physiologically balanced state, the immune system is able to resume its function of protecting the body and initiating the healing process. With renewal of the normal inflammatory process, the regenerative processes of the immune system are again allowed to function.
Restoring Immunostasis As noted, the clearance of excessive cytokines, the clearance of proteins and peptides damaged by inflammation, the inactivation of AGEs, and the inactivation of adhesion molecules in inflamed and malignant cells are all mediated by proteolytic enzymes.
A balanced immune system Phlogenzym Prostatitis immunostasis — can be manifested by using systemic enzyme support, which provides the essential proteolytic enzymes. Systemic enzyme support can be defined as a treatment modality that Phlogenzym Prostatitis oral administration of exogenous hydrolytic mainly proteolytic enzymes of animal origin trypsin, chymotrypsin Phlogenzym Prostatitis plant origin bromelain, papain in the form of enteric-coated tablets for supporting healthy and normal inflammatory processes in Phlogenzym Prostatitis body.
Systemic enzyme support using Wobenzym N and Wobenzym PS is able to influence immunity in such a fashion as to reduce pain, swelling, inflammation, Phlogenzym Prostatitis and lymphedema, and increase fibrinolysis, and the clearance of harmful immune complexes that are a result of antibody reactions.
Systemic enzyme support provides enzymes that can be utilized to assist the body's various regulatory and communications systems and supports the function of tissues at a cellular level. Systemic Phlogenzym Prostatitis support has Phlogenzym Prostatitis for degenerative and autoimmune diseases, and as an adjuvant to improve efficacy of anti-infectives in infectious diseases.
Conditions Treated with Systemic Enzyme Phlogenzym Prostatitis Based on clinical observations and literature review, systemic enzyme support effectively improves the treatment of conditions with an autoaggressive component by promoting the decomposition and elimination of disease-associated CICs.
Clinical improvement is noted in a wide range of conditions, with benefits observed in treating various body systems. Nervous system disorders such as multiple sclerosis showed a Phlogenzym Prostatitis in number and duration of attacks because of decreased inflammatory activity due to systemic enzyme support.
Researchers have concluded that systemic enzyme support Phlogenzym Prostatitis a novel therapeutic modality that helps in treating children showing a high sickness rate, and noted that the number Phlogenzym Prostatitis severity of dyspnea attacks decreased in children with proven asthma.
The inclusion of systemic enzyme support in treatment of psoriasis significantly decreases the exudative component of exacerbation, increased regression, and decreases recurrence. There are also positive clinicolaboratory results that considerably Phlogenzym Prostatitis those for conventional drug treatment in patients with pyelonephritis.
It is an important part of the complex therapy of male and female sterility, recurrent miscarriages, and chronic infections of the reproductive system. Systemic enzyme support is an effective immunomodulator for both autoimmune and alloimmune infertility. It is an effective and safe alternative to NSAIDS non-steroidal anti-inflammatory drugs in the treatment of painful episodes of osteoarthritis of the knee and hip.
In addition to osteoarthritis, rheumatoid arthritis, gouty arthridities, and juvenile arthritis, systemic enzyme support has also Phlogenzym Prostatitis shown as effective in the Phlogenzym Prostatitis of psoriatic arthritis. It is fair to say that systemic enzyme support could be used in any form of arthritis. Sports Phlogenzym Prostatitis is another area in which systemic enzyme support excels.
Sport- and exercise-related muscle pain and inflammation provoked by a strong physical Phlogenzym Prostatitis, excessive training, and heavy competition Phlogenzym Prostatitis are decreased Phlogenzym Prostatitis "excellent results" due to the selective interferences Phlogenzym Prostatitis enzymes with the pathophysiologic mechanisms of exercise-induced inflammation. Systemic enzyme support also improves recovery from sprains, as well as shortens recovery from sport injuries severe enough to require surgery.
Biomarkers of Inflammation and Systemic Enzyme Support It is again important to note that the studies showing clinical efficacy in the aforementioned conditions are based on the enteric coated polyenzyme formulations that originated from Germany. Clinicians can be confident that they will observe Phlogenzym Prostatitis same degree of clinical Phlogenzym Prostatitis with Wobenzym Phlogenzym Prostatitis and Wobenzym PS, which are manufactured in Germany by that company.
As well as the clinically observable benefits, systemic enzyme support improves or normalizes the levels of several biomarkers of inflammation, as mentioned above. Conclusion Systemic enzyme support has been demonstrated to be an effective treatment either as primary therapy or adjuvant therapy that improves clinical outcomes of diseases that are difficult to manage.
Systemic enzyme support has been reported to have excellent tolerance and superior safety when compared with some conventional therapies. This significant compliance to systemic enzyme support is believed to be primarily due to its effectiveness.
More information can be found at www. Notes 1. Conformation and protease binding activity of binary and ternary human alpha 2-macroglobulin-protease complexes. J Biol Chem. Cytokine binding and clearance properties of proteinase-activated alpha 2-macroglobulins. Lab Invest. Protease activation of alpha2-macroglobulin modulates a chaperone-like action Phlogenzym Prostatitis broad specificity.
Alpha 2-macroglobulin-mediated degradation of amyloid beta 1— Phlogenzym Prostatitis mechanism to enhance amyloid beta catabolism. Exp Neurol. Degradation of amyloid Phlogenzym Prostatitis by a serine protease-alpha2-macroglobulin Phlogenzym Prostatitis. Ligation of cell surface-associated glucose-regulated protein 78 by receptor-recognized forms of alpha 2-macroglobulin: activation of pactivated protein kinasedependent signaling in murine peritoneal macrophages.
J Immunol. In vitro binding and in vivo clearance of human alpha 2-macroglobulin after reaction with endoproteases from four different classes.
Biochem Biophys Res Commun. Use of oral enzymes in multiple sclerosis patients. Int J Tissue React. Lauer D et al. Systemic enzyme treatment as a method of secondary prevention in patients after myocardial Phlogenzym Prostatitis in the rehabilitation period. Abstracts: — KA Systemic enzyme therapy in the complex treatment of angina pectoris. Int J Immunother. Application of Wobenzym and Phlogenzym to the angiology and vascular surgery. Georgian Med News. Systemic enzyme therapy of lower limb postphlebitic syndrome.
Angiol Sosud Khir. Wald M. Diagnosis and treatment of lymphedema. Systemic enzyme therapy in the treatment of children with recurrent infections of Phlogenzym Prostatitis tract.