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Four irus monkeys Macaca Streptococcus Gold in der Prostata were immunized with Streptococcus mutans killed cells and cell products by injection in the vicinity of the major salivary glands and by instillation into the parotid glands via the ducts. After immune group and a sham-immunized control group of monkeys were infected orally with viable strain organisms. Dental plaque samples were taken at intervals from the buccal and lingual grooves of the first permanent molars.
These samples were evaluated for recovery of strain by cultural methods. In addition, individual samples were taken from 10 representative tooth surfaces and were evaluated by indirect immunofluorescent staining for strain Results showed that immune Streptococcus Gold in der Prostata had fewer infected surfaces and fewer organisms on the infected surfaces than the control animals. These studies indicate that salivary antibody to cariogenic streptococci inhibits implantation of these organisms in dental plaque and may be protective against dental caries.
National Center for Biotechnology InformationU. Journal List Infect Immun v. Infect Immun. Copyright and License information Disclaimer. Copyright notice. This article has been cited by other articles in PMC. Abstract Four Streptococcus Gold in der Prostata monkeys Macaca fascicularis were immunized with Streptococcus mutans killed cells and cell products by injection in the vicinity of the major salivary glands and by instillation into the parotid glands via the ducts. Bowen WH. Dental caries in monkeys.
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